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The impaired adipogenesis is associated with stress of the endoplasmic reticulum (ER) and elevated expression of unfolded protein response (UPR), both can exacerbate the proinflammatory phenotype of preadipocytes and adipocytes [58]

Principal component and differential expression analysis Following the normalization of gene hit counts, the results underwent principal component analysis using the top 2,000 genes with the highest variance

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We've reviewed reconstitution logs from research teams and the pattern is consistent

Methione: An essential amino acid, meaning that it cannot be synthesized in the body